Department Publications

Objective Young children and infants, especially newborns, are highly susceptible to seizures, which, if undetected and untreated, can lead to severe long-term neurological consequences. Early detection typically requires continuous electroencephalography (cEEG) monitoring in hospital settings, involving costly equipment and highly trained specialists. This study presents a low-cost, active dry-contact electrode–based, adjustable electroencephalography (EEG) headset, combined with an explainable deep learning model for seizure detection from reduced-montage EEG, and a multimodal artifact removal algorithm to enhance signal quality. Methods EEG signals were acquired via active electrodes and processed through a custom-designed analog front end for filtering and digitization. The adjustable headset was fabricated using three-dimensional printing and laser cutting to accommodate varying head sizes …

Objective Neonates are highly susceptible to seizures, which can have severe long-term consequences if undetected and left untreated. Early detection is crucial and typically requires continuous electroencephalography (EEG) monitoring in a hospital setting, which is costly, inconvenient, and requires specialized experts for diagnosis. In this work, we propose a new low-cost active dry-contact electrode-based adjustable EEG headset, a new explainable deep learning model to detect neonatal seizures, and an advanced signal processing algorithm to remove artifacts to address the key aspects that lead to the underdiagnosis of neonatal seizures. Methods EEG signals are acquired through active electrodes and processed using a custom-designed analog front end (AFE) that filters and digitizes the captured EEG signals. The adjustable headset is designed using three-dimensional (3D) printing and laser cutting to …

This review outlines the current status and proposes future directions for using auditory brainstem responses (ABRs) to continuous speech as a tool in hearing aid assessment. In current clinical practice, ABRs measured via electroencephalography (EEG) in response to short stimuli, averaged across repetitions, are a cornerstone of objective hearing screening and evaluation. Recent advancements have demonstrated that ABRs can be estimated from EEG recorded during continuous speech listening by using linear models which map the auditory speech features, extracted using auditory models, to continuous EEG activity. This approach enables the simultaneous investigation of multiple auditory pathway stages using complex, ecologically valid sounds; advancing potential future hearing assessments that can be seamlessly integrated into daily life. Current findings indicate that responses similar to click-ABRs …

Cardiac auscultation is an essential clinical skill, requiring excellent hearing to distinguish subtle differences in timing and pitch of heart sounds. However, diagnosing solely from these sounds is often challenging due to interference from surrounding noise, and the information may be limited. Most of the existing solutions that adaptively cancel external noise are either non-real-time or computationally intensive, making them unsuitable for implementation in a portable system. This work proposes an end-to-end system with a real-time adaptive noise cancellation pipeline integrated into a device that simultaneously acquires electrocardiogram (ECG) and phonocardiogram (PCG) signals. We employ a burst adaptive normalized least mean square algorithm that adjusts its adaptation in response to high-energy, non-stationary hospital noise. The algorithm's performance was initially assessed using datasets with artificially induced noise. Subsequently, the complete end-to-end system was validated using real-world hospital recordings captured with the dual-modality device. For PCG and ECG signals recorded from the device in noisy hospital settings, the proposed system achieved signal-to-noise ratio improvements of 37.01 dB and 30.32 dB, respectively. Furthermore, complexity analysis confirms the pipeline's suitability for embedded implementation. These results demonstrate the system's effectiveness in enabling reliable and accessible cardiac screening in noisy hospital environments typical of resource-constrained settings.